PhD position in Molecular Parasitology

Pracoviště:

Parazitologický ústav

Oddělení:

Molekulární parazitologie

Laboratoř:

Laboratoř funkční biologie protist

Pracovněprávní vztah:

Pracovní smlouva

Typ pracovní pozice:

Vědecká

Vědecký profil:R1

Doba trvání:

Doba určitá

Pracovní úvazek:

Plný

Datum nástupu:

1. 1. 2021

Uzávěrka přihlášek:

30. 9. 2020

Popis pracovní pozice:

We are seeking a highly motivated individual to join our team working on the unique traits of mitochondrial ribosomes and translation of Trypanosoma brucei, the causative agent of the sleeping sickness. Ribosomes, highly conserved machines fundamental for all life forms, were recently shown to undergo unexpected diversification in endosymbiotic organelles with vestigial genomes. The most divergent ribosomes are found in the mitochondria of parasitic protists from the group of Kinetoplastids, including trypanosomes. In this project, we complement the wealth of structural information on mitoribosomes and their precursors obtained by cryoEM with functional approaches to get detailed insight into lineage specific features of translation in mitochondria of trypanosomes. We aim to understand how the divergent mitoribosomes co-evolved with the peculiar context of the mitochondrial gene expression in the parasite. We offer: • Work with organism with unique molecular and cellular processes and medical importance • Modern techniques of molecular and structural biology and biochemistry • Well-equipped laboratory with friendly and international team • Opportunities to present advances of the project on conferences, network of international collaborations • Scholarship and partial appointment together fully covering living expenses for at least 3 years

Požadavky:

Min. úroveň vzdělání:

Magisterské

Obor vzdělání:

Biology, Biochemistry, or related field

We expect: • MSc degree or equivalent from Biology, Biochemistry, or related field • Enthusiasm, commitment and team spirit • Good English communication skills

Benefity:

• 5 weeks of holiday • Friendly international working environment • Subsidized lunch • Benefits from Social Fund • Support of leisure time activities

Doplňující informace:

The successful applicant will work under the supervision of Ondrej Gahura in the Laboratory of Functional Biology of Protist led by Alena Zíková, at the Institute of Parasitology, Biology Centre of the Czech Academy of Science in Ceske Budejovice (Budweiss), Czech Republic. Our institute is located in the joint campus of Czech Academy and Science and University of Science Bohemia, providing an international and multidisciplinary scientific environment. The historic city of Ceske Budejovice (population 100.000), famous for its Budweiser beer, is a pleasant, safe and affordable place for living, and offers a wide range of freetime activities. The BC CAS is a holder of the HR Excellence in Research Award. Our selection process is transparent, open, non-discriminating and fair. For more information about the researchers recruitment policy at our institution, see www.bc.cas.cz/en/about-us/employment/. To apply, send a cover letter, CV and at least one reference contact via the "REPLY" button below.

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